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In vivo engineering of CAR natural killer cells for immunotherapy using ligand-directed lipid nanoparticles

INVESTOR TAKEAWAY

Nature Biotechnology, Published online: 13 October 2026; doi:10.1038/s41587-026-03310-1 Chimeric antigen receptor natural killer cells to treat autoimmune disease and cancer are generated in vivo.

ORIGINAL PAPER

In vivo engineering of CAR natural killer cells for immunotherapy using ligand-directed lipid nanoparticles

WHAT WE KNOW

Nature Biotechnology, Published online: 13 October 2026; doi:10.1038/s41587-026-03310-1 Chimeric antigen receptor natural killer cells to treat autoimmune disease and cancer are generated in vivo.

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